Biotechnological applications of a crude enzymatic extract from Penicillium brevicompactum
Biorremediationo; Antibiotic; Microorganisms; Agricultural defensive; sub-product
Penicillium brevicompactum is a versatile fungal strain known for its ability to produce a variety of metabolites, particularly enzymes. However, there is limited research on the specific enzymes it produces. Fungal strains are valuable in solid-state fermentation, especially for transforming agricultural waste into valuable byproducts. In this study, we explored the potential applications of a crude fermented extract from P. brevicompactum, which was obtained through solid-state fermentation using sugarcane bagasse (SCB). We observed both structural and chemical modifications in SCB during the fermentation process. By employing response surface methodology, we optimized the production of cell-wall degrading enzymes. After seven days of fermentation at 65% moisture, P. brevicompactum produced avicelase, β-glucosidase, xylanase, carboxymethylcellulase, laccase, manganese peroxidase, and lignin peroxidase.
These enzymes have demonstrated the ability to degrade organic micropollutants and inhibit the growth of fungi and nematodes. Therefore, we conclude that the crude fermented extract can be effectively used for various purposes, including biological control and bioremediation, which support a circular economy and align with the biorefinery concept.