Bats and zoonotic bacterial pathogens: a One Health approach
Zoonoses, Quiroptéros, Bacterial Pathogens, One Health.
Zoonotic diseases cause great impacts on public health, generate economic losses and can also affect the conservation of species. The bats, represented by bats, have gained prominence as a potential transmitter of various diseases, especially bacterial zoonoses. Thus, the aim of this dissertation was to contribute to the knowledge of the role of these animals in the cycle of zoonotic diseases, especially their importance as a carrier of bacterial pathogens. For this, a systematic review of zoonotic bacterial pathogens found in bats was carried out, and a cross-sectional study investigating the presence of Brucella spp., Leptospira spp. and Salmonella spp in bats from Montes Claros, Minas Gerais, Brazil. The systematic review followed the guidelines recommended by PRISMA. One hundred and three bacterial genera were detected in several families of bats surveyed around the world, in a variety of clinical samples (blood, heart, lung, kidney, liver, spleen, feces, saliva, skin, among others). In the cross-sectional study, the investigation of the DNA of pathogens was carried out using molecular biology techniques in blood, liver and spleen samples of bats from the urban and wild area of Montes Claros, and the presence of DNA from Salmonella spp. in a blood sample of an insectivorous female bat of the species Lasiurus blossevilli, evidencing the capacity of this animal species to host this pathogen. Overall, our results showed that bats harbor numerous bacterial pathogens. More studies are needed to elucidate the importance of bats as potential transmitters of these pathogens, for the determination of preventive measures considering the context of One Health.